Renal tubular acidosis
Renal tubular acidosis (PKA)- A group of disorders characterized by impaired oxidative mechanisms in the renal tubules with the intact functions of the glomerular apparatus, which leads to metabolic acidosis. These disorders are divided into 3 types.
PKA-1: classical, distal, hypokalemic (due to the improbability of maintaining the ionic gradient H +).
- PKA-2: proximal (due to reduced reabsorption of bicarbonate), reabsorption in the distal tubule is not disturbed.
- PKA-4: generalized, distal, hyperkalemic (due to primary or secondary aldosterone deficiency or resistance to it).